BDBM50326203 CHEMBL1243073::N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-3-phenoxybenzamide

SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(NC(=O)c2cccc(Oc3ccccc3)c2)cc1C

InChI Key InChIKey=GASPHORHXIOCBB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326203   

TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326203(CHEMBL1243073 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataEC50: >1.20E+3nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326203(CHEMBL1243073 | N-(3-Methyl-4-(3-(2-(methylamino)p...)
Affinity DataIC50:  251nMAssay Description:Inhibition of Aurora B by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed