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BDBM50326427 (4-Fluoro-phenyl)-(9H-purin-6-yl)-amine::CHEMBL361227::N-(4-fluorophenyl)-9H-purin-6-amine

InChI string: InChI=1S/C11H8FN5/c12-7-1-3-8(4-2-7)17-11-9-10(14-5-13-9)15-6-16-11/h1-6H,(H2,13,14,15,16,17)

SMILES: Fc1ccc(Nc2ncnc3nc[nH]c23)cc1

InChI Key: InChIKey=SCRHVVOELSYCSO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326427   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-interacting serine/threonine-protein kinase MNK1


(Homo sapiens (human))
BDBM50326427
PNG
((4-Fluoro-phenyl)-(9H-purin-6-yl)-amine | CHEMBL36...)
Show SMILES Fc1ccc(Nc2ncnc3nc[nH]c23)cc1
Show InChI InChI=1S/C11H8FN5/c12-7-1-3-8(4-2-7)17-11-9-10(14-5-13-9)15-6-16-11/h1-6H,(H2,13,14,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.03E+3n/an/an/an/an/an/a



Spanish National Cancer Research Centre (CNIO)

Curated by ChEMBL


Assay Description
Inhibition of MNK1


J Med Chem 53: 6618-28 (2010)

More data for this
Ligand-Target Pair