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BDBM50326566 2-hydroxy-3-(pyridin-2-yl)propanoic acid::CHEMBL1253274

SMILES: OC(Cc1ccccn1)C(O)=O

InChI Key: InChIKey=RAOAWTKYEHBLHT-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326566   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine phosphatase alpha


(Homo sapiens (Human))
BDBM50326566
PNG
(2-hydroxy-3-(pyridin-2-yl)propanoic acid | CHEMBL1...)
Show SMILES OC(Cc1ccccn1)C(O)=O
Show InChI InChI=1/C8H9NO3/c10-7(8(11)12)5-6-3-1-2-4-9-6/h1-4,7,10H,5H2,(H,11,12)
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CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.80E+4n/an/an/an/a7.0n/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7


Bioorg Med Chem 18: 5449-56 (2010)


Article DOI: 10.1016/j.bmc.2010.04.050
BindingDB Entry DOI: 10.7270/Q2Q52QMC
More data for this
Ligand-Target Pair