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BDBM50326824 1-(5-chloro-2-methoxyphenyl)-3-(2-methyl-1,7-naphthyridin-4-yl)urea::CHEMBL1254618

SMILES: COc1ccc(Cl)cc1NC(=O)Nc1cc(C)nc2cnccc12

InChI Key: InChIKey=ZTOKFELFUNZUEO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326824   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50326824
PNG
(1-(5-chloro-2-methoxyphenyl)-3-(2-methyl-1,7-napht...)
Show SMILES COc1ccc(Cl)cc1NC(=O)Nc1cc(C)nc2cnccc12
Show InChI InChI=1S/C17H15ClN4O2/c1-10-7-13(12-5-6-19-9-15(12)20-10)21-17(23)22-14-8-11(18)3-4-16(14)24-2/h3-9H,1-2H3,(H2,20,21,22,23)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



San Francisco State University

Curated by ChEMBL


Assay Description
Inhibition of recombinant IGF1R by ELISA


Bioorg Med Chem 18: 5995-6005 (2010)


Article DOI: 10.1016/j.bmc.2010.06.071
BindingDB Entry DOI: 10.7270/Q27944WQ
More data for this
Ligand-Target Pair