BDBM50327419 1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(pyridin-4-yl)urea::CHEMBL1258517

SMILES: O=C(Nc1ccncc1)Nc1ccc(cc1)-c1nc(nc(n1)N1CCOCC1)N1C2CCC1COC2

InChI Key: InChIKey=WXUUCRLKXQMWRY-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50327419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2A6 (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2B6 (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50327419 (1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-mo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
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