BDBM50327571 6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)propoxy)isoindolin-1-one::CHEMBL1258880

SMILES Fc1ccc2c(cccc2c1)N1CCN(CCCOc2ccc3CNC(=O)c3c2)CC1

InChI Key InChIKey=WMTJVDAYQLPIMI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327571   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327571(6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  1.54nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327571(6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  3.54nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327571(6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  44.5nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50327571(6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  439nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed