BDBM50327574 7-fluoro-6-(3-(4-(6-fluoronaphthalen-1-yl)piperazin-1-yl)propoxy)isoindolin-1-one::CHEMBL1258314

SMILES Fc1ccc2c(cccc2c1)N1CCN(CCCOc2ccc3CNC(=O)c3c2F)CC1

InChI Key InChIKey=QCIZDOBRHYWEBN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50327574   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327574(7-fluoro-6-(3-(4-(6-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  3.04nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327574(7-fluoro-6-(3-(4-(6-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  5.41nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327574(7-fluoro-6-(3-(4-(6-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  8.59nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327574(7-fluoro-6-(3-(4-(6-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  24.7nMAssay Description:Displacement of [3H]-citalopram from human serotonin transporter expressed in HEK 293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327574(7-fluoro-6-(3-(4-(6-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  37.4nMAssay Description:Displacement of [3H]-citalopram from human serotonin transporter expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed