BDBM50327577 7-fluoro-6-(4-(4-(7-fluoronaphthalen-1-yl)piperazin-1-yl)butoxy)isoindolin-1-one::CHEMBL1258313

SMILES Fc1ccc2cccc(N3CCN(CCCCOc4ccc5CNC(=O)c5c4F)CC3)c2c1

InChI Key InChIKey=PFCBMQJUWYAJDO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327577   

Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327577(7-fluoro-6-(4-(4-(7-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327577(7-fluoro-6-(4-(4-(7-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  4.56nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327577(7-fluoro-6-(4-(4-(7-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  5.75nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327577(7-fluoro-6-(4-(4-(7-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  259nMAssay Description:Displacement of [3H]-citalopram from human serotonin transporter expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed