BDBM50327587 7-chloro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)propoxy)isoindolin-1-one::CHEMBL1257146

SMILES Fc1cccc2cccc(N3CCN(CCCOc4ccc5CNC(=O)c5c4Cl)CC3)c12

InChI Key InChIKey=UWMMCCDYCWFBFZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327587   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327587(7-chloro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  0.312nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327587(7-chloro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  3.55nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327587(7-chloro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  9.01nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327587(7-chloro-6-(3-(4-(8-fluoronaphthalen-1-yl)piperazi...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]-citalopram from human serotonin transporter expressed in HEK 293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed