BindingDB logo
myBDB logout

BDBM50327723 4-((1-octyl-5-m-tolyl-1H-indol-3-yl)methyl)morpholine::CHEMBL1257160

SMILES: CCCCCCCCn1cc(CN2CCOCC2)c2cc(ccc12)-c1cccc(C)c1

InChI Key: InChIKey=WBYNRAKSMBJLNM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327723   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Isoprenylcysteine carboxyl methyltransferase


(Homo sapiens (Human))
BDBM50327723
PNG
(4-((1-octyl-5-m-tolyl-1H-indol-3-yl)methyl)morphol...)
Show SMILES CCCCCCCCn1cc(CN2CCOCC2)c2cc(ccc12)-c1cccc(C)c1
Show InChI InChI=1S/C28H38N2O/c1-3-4-5-6-7-8-14-30-22-26(21-29-15-17-31-18-16-29)27-20-25(12-13-28(27)30)24-11-9-10-23(2)19-24/h9-13,19-20,22H,3-8,14-18,21H2,1-2H3
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



National University of Singapore

Curated by ChEMBL


Assay Description
Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting


J Med Chem 53: 6838-50 (2010)


Article DOI: 10.1021/jm1002843
BindingDB Entry DOI: 10.7270/Q2VT1SB1
More data for this
Ligand-Target Pair