BDBM50327811 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(1-propionylpiperidin-4-yl)urea::CHEMBL1258669::US9296693, 35

SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=ONNVDWDSGPRNRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327811   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327811(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(1-propio...)
Affinity DataIC50:  4.10nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327811(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(1-propio...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327811(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(1-propio...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327811(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(1-propio...)
Affinity DataIC50:  2.30nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent