BDBM50328054 3-(1-((2R,3S)-3-acetamido-4-(3,5-difluorophenyl)-2-hydroxybutylamino)cyclopropyl)-5-neopentylpyridine 1-oxide::CHEMBL1257533

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CC1)c1cc(CC(C)(C)C)c[n+]([O-])c1

InChI Key InChIKey=KZOWDSWZTVEAML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328054   

TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328054(3-(1-((2R,3S)-3-acetamido-4-(3,5-difluorophenyl)-2...)
Affinity DataIC50: 720nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328054(3-(1-((2R,3S)-3-acetamido-4-(3,5-difluorophenyl)-2...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed