BDBM50328076 6-(1H-indazol-4-yl)-N-(3-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1257186

SMILES COc1cccc(Nc2nc(nc3n(C)ncc23)-c2cccc3[nH]ncc23)c1

InChI Key InChIKey=YKEGMKBGSDKZQJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328076   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50328076(6-(1H-indazol-4-yl)-N-(3-methoxyphenyl)-1-methyl-1...)Copy SMILESCopy InChI

Affinity DataIC50:  1.40nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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