BDBM50328152 CHEMBL1257423::N-(2-hydroxyethyl)-3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide::US11649218, Example GNF-5

SMILES: OCCNC(=O)c1cccc(c1)-c1cc(Nc2ccc(OC(F)(F)F)cc2)ncn1

InChI Key: InChIKey=IIQUYGWWHIHOCF-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Human)	BDBM50328152 (N-(2-hydroxyethyl)-3-(6-(4-(trifluoromethoxy)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	935	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50328152 (N-(2-hydroxyethyl)-3-(6-(4-(trifluoromethoxy)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50328152 (N-(2-hydroxyethyl)-3-(6-(4-(trifluoromethoxy)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50328152 (N-(2-hydroxyethyl)-3-(6-(4-(trifluoromethoxy)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50328152 (N-(2-hydroxyethyl)-3-(6-(4-(trifluoromethoxy)pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair