BDBM50328159 6-(1-(pyridin-3-ylmethyl)-1H-pyrazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)pyrimidin-4-amine::CHEMBL1257897::US9670214, TABLE 16.68

SMILES: FC(F)(F)Oc1ccc(Nc2cc(ncn2)-c2cnn(Cc3cccnc3)c2)cc1

InChI Key: InChIKey=NEVWISPIZUUKHD-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-specific protein-tyrosine kinase (Human)	BDBM50328159 (6-(1-(pyridin-3-ylmethyl)-1H-pyrazol-4-yl)-N-(4-(t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	7.5	n/a
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Non-specific protein-tyrosine kinase [T818I] (Human)	BDBM50328159 (6-(1-(pyridin-3-ylmethyl)-1H-pyrazol-4-yl)-N-(4-(t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50328159 (6-(1-(pyridin-3-ylmethyl)-1H-pyrazol-4-yl)-N-(4-(t...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair