BDBM50328301 4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propoxy)-2-(hydroxymethyl)phenol::CHEMBL1257555

SMILES OCc1cc(OCC(O)CNC2CCN(CC2)c2ncnc3scc(-c4ccccc4)c23)ccc1O

InChI Key InChIKey=KYYMUHCVQBBYFP-UHFFFAOYSA-N

Data  3 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50328301   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328301(4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328301(4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328301(4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataKi:  629nMAssay Description:Agonist activity at human recombinant adrenergic beta-1 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328301(4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataEC50:  0.0200nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328301(4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataIC50:  2.25E+3nMAssay Description:Antagonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as inhibition of isoproterenol-induced cyclic AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50328301(4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at human recombinant adrenergic beta1 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed