BDBM50328347 CHEMBL1257800::diethyl 2-morpholino-4-phenyl-7-(3,3,3-trifluoropropyl)pyrrolo[1,2-b]pyridazine-5,6-dicarboxylate

SMILES CCOC(=O)c1c(CCC(F)(F)F)n2nc(cc(-c3ccccc3)c2c1C(=O)OCC)N1CCOCC1

InChI Key InChIKey=YQOCGVRFFGLKAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328347   

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328347(diethyl 2-morpholino-4-phenyl-7-(3,3,3-trifluoropr...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328347(diethyl 2-morpholino-4-phenyl-7-(3,3,3-trifluoropr...)
Affinity DataIC50: 920nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed