BDBM50328384 CHEMBL1257209::ethyl 2-morpholino-4-phenyl-7-propyl-6-(3-(pyrrolidin-1-yl)-1,2,4-oxadiazol-5-yl)pyrrolo[1,2-b]pyridazine-5-carboxylate

SMILES CCCc1c(-c2nc(no2)N2CCCC2)c(C(=O)OCC)c2c(cc(nn12)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=NBXLBDCDGRUOCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328384   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328384(CHEMBL1257209 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  100nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328384(CHEMBL1257209 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  770nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328384(CHEMBL1257209 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed