BDBM50328454 1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butan-1-one::CHEMBL1258270

SMILES Cc1ccc(C)c(c1)C1CCN(CCCC(=O)c2cc(C)ccc2C)CC1

InChI Key InChIKey=QPOPFNWPFQDIQV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328454   

TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328454(1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)pi...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328454(1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)pi...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328454(1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)pi...)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328454(1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)pi...)
Affinity DataKi:  5.70E+3nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2 receptor in pig cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328454(1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)pi...)
Affinity DataKi:  9.00E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed