BDBM50328518 CHEMBL1259081::syn-2-amino-5-oxo-4,7-diphenyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile

SMILES N=C1OC2=C([C@@H](C1C#N)c1ccccc1)C(=O)N[C@H](C2)c1ccccc1

InChI Key InChIKey=GFBLCEMDXOXZMD-WOEZKJSCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328518   

TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328518(CHEMBL1259081 | syn-2-amino-5-oxo-4,7-diphenyl-5,6...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328518(CHEMBL1259081 | syn-2-amino-5-oxo-4,7-diphenyl-5,6...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed