BDBM50328639 (3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-methanone::(3-chloro-4-fluorophenyl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone::Befiradol::CHEMBL45305::US10562853, Compound Befiradol

SMILES: Cc1ccc(nc1)CNCC2(CCN(CC2)C(=O)c3ccc(c(c3)Cl)F)F

InChI Key: InChIKey=PKZXLMVXBZICTF-UHFFFAOYSA-N

Data: 11 KI  2 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50328639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Pig)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Pig)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50328639 ((3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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