BDBM50328755 2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido)-1H-pyrazol-1-yl)phenyl)acetamide::CHEMBL1271376

SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(n1)-c1cccc(CC(N)=O)c1

InChI Key InChIKey=ZJQYVSTVRXOFQL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328755   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CRAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50:  9nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetEphrin type-B receptor 2(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50:  82nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50:  17nMAssay Description:Inhibition of BRAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50:  11nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB