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BDBM50328836 4-(6-chloro-2-methoxyacridin-9-ylamino)benzoic acid::CHEMBL533642::NSC-11404

SMILES: COc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(cc3)C(O)=O)c2c1

InChI Key: InChIKey=JUEVEQFGSFHEFN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328836   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PH domain leucine-rich repeat-containing protein phosphatase 2


(Homo sapiens (Human))
BDBM50328836
PNG
(4-(6-chloro-2-methoxyacridin-9-ylamino)benzoic aci...)
Show SMILES COc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(cc3)C(O)=O)c2c1
Show InChI InChI=1S/C21H15ClN2O3/c1-27-15-7-9-18-17(11-15)20(16-8-4-13(22)10-19(16)24-18)23-14-5-2-12(3-6-14)21(25)26/h2-11H,1H3,(H,23,24)(H,25,26)
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PC sid
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Similars

Article
PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



University of California San Diego

Curated by ChEMBL


Assay Description
Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coli


J Med Chem 53: 6899-911 (2010)


Article DOI: 10.1021/jm100331d
BindingDB Entry DOI: 10.7270/Q2154H8Z
More data for this
Ligand-Target Pair