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BDBM50328837 2-hydroxy-5-((4'-((1-hydroxy-3-(methylsulfonyl)-7-(phenylamino)naphthalen-2-yl)diazenyl)biphenyl-4-yl)diazenyl)benzoic acid::CHEMBL1269667::NSC-47760

SMILES: CS(=O)(=O)c1cc2ccc(Nc3ccccc3)cc2c(O)c1N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O

InChI Key: InChIKey=ZDUJSIQADFMAOQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328837   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PH domain leucine-rich repeat-containing protein phosphatase 2


(Homo sapiens (Human))
BDBM50328837
PNG
(2-hydroxy-5-((4'-((1-hydroxy-3-(methylsulfonyl)-7-...)
Show SMILES CS(=O)(=O)c1cc2ccc(Nc3ccccc3)cc2c(O)c1N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O
Show InChI InChI=1S/C36H27N5O6S/c1-48(46,47)33-19-24-11-16-28(37-25-5-3-2-4-6-25)20-30(24)35(43)34(33)41-39-27-14-9-23(10-15-27)22-7-12-26(13-8-22)38-40-29-17-18-32(42)31(21-29)36(44)45/h2-21,37,42-43H,1H3,(H,44,45)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



University of California San Diego

Curated by ChEMBL


Assay Description
Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coli


J Med Chem 53: 6899-911 (2010)


Article DOI: 10.1021/jm100331d
BindingDB Entry DOI: 10.7270/Q2154H8Z
More data for this
Ligand-Target Pair