BDBM50328865 (3S,4R)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cyclopropyl-4-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)-4-hydroxypiperidine-3-carboxamide::CHEMBL1269699

SMILES COCCc1ccc(Cl)c(CN(C2CC2)C(=O)[C@H]2CNCC[C@]2(O)c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c1

InChI Key InChIKey=XQJYPYVXYANJRR-MYVCOICNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328865   

TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328865((3S,4R)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328865((3S,4R)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328865((3S,4R)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328865((3S,4R)-N-(2-chloro-5-(2-methoxyethyl)benzyl)-N-cy...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed