BDBM50328881 4-(3-hydroxypropyl)-6-(3-(trifluoromethyl)phenyl)pyrimidine-2-carbonitrile::CHEMBL1271273

SMILES OCCCc1cc(nc(n1)C#N)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=JPCVMZOWQLMUNJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328881   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328881(4-(3-hydroxypropyl)-6-(3-(trifluoromethyl)phenyl)p...)
Affinity DataKi:  3.10E+4nMAssay Description:Displacement of [3H] dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328881(4-(3-hydroxypropyl)-6-(3-(trifluoromethyl)phenyl)p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant cathepsin K using Z-Phe-Arg-MCA substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed