BDBM50328894 2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimidin-4-yl)propylamino)-2-methylpropanamide::CHEMBL1270269

SMILES: CC(C)(NCCCc1cc(nc(n1)C#N)-c1cccc(c1)C(F)(F)F)C(N)=O

InChI Key: InChIKey=XCVJGPONRKMMGU-UHFFFAOYSA-N

Data: 2 KI  8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50328894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50328894 (2-(3-(2-cyano-6-(3-(trifluoromethyl)phenyl)pyrimid...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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