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BDBM50328935 (4-isopropylpiperazin-1-yl)(1-(methylsulfonyl)-3-(piperidin-1-ylmethyl)-1H-indol-6-yl)methanone::CHEMBL1271072

SMILES: CC(C)N1CCN(CC1)C(=O)c1ccc2c(CN3CCCCC3)cn(c2c1)S(C)(=O)=O

InChI Key: InChIKey=GHFVTTNBOLMPRU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328935   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50328935
PNG
((4-isopropylpiperazin-1-yl)(1-(methylsulfonyl)-3-(...)
Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2c(CN3CCCCC3)cn(c2c1)S(C)(=O)=O
Show InChI InChI=1S/C23H34N4O3S/c1-18(2)25-11-13-26(14-12-25)23(28)19-7-8-21-20(16-24-9-5-4-6-10-24)17-27(22(21)15-19)31(3,29)30/h7-8,15,17-18H,4-6,9-14,16H2,1-3H3
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PC cid
PC sid
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Patents

Article
PubMed
1.90n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...


Bioorg Med Chem Lett 20: 6226-30 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.103
BindingDB Entry DOI: 10.7270/Q2CF9QB3
More data for this
Ligand-Target Pair