BDBM50329059 CHEMBL1236772::GTC000121A::N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine::N^4^-1H-INDAZOL-4-YL-N^2^-[3-(METHYLSULFONYL)PHENYL]PYRIMIDINE-2,4-DIAMINE

SMILES: CS(=O)(=O)c1cccc(c1)Nc2nccc(n2)Nc3cccc4c3cn[nH]4

InChI Key: InChIKey=FIWCLCRWDUELGO-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50329059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM50329059 (N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65.2	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK [355-635] (Human)	BDBM50329059 (N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM50329059 (N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Human)	BDBM50329059 (N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	547	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 4 (Human)	BDBM50329059 (N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Human)	BDBM50329059 (N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair