BDBM50329179 2-((4S)-4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepin-6(5H)-yl)-N-benzyl-N-isopropylacetamide::CHEMBL1269258
SMILES CC(C)N(Cc1ccccc1)C(=O)CN1c2ccccc2-n2c(nnc2-c2ccccc2)[C@H](Cc2c[nH]c3ccccc23)C1=O
InChI Key InChIKey=UBNMGTSDHSQBEL-PMERELPUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 57 hits for monomerid = 50329179
Affinity DataKi: 25nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK2R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 275nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 427nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK2R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Partial agonist activity at wild-type human CCK2R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at wild-type human CCK1R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.51nMAssay Description:Agonist activity at wild-type human CCK1R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 0.525nMAssay Description:Agonist activity at human CCK1R N2.61T mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human CCK1R T3.28V, T3.29S mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Agonist activity at human CCK1R I6.51V, F6.52Y mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R T2.61N mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R V3.28T, S3.29T mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 282nMAssay Description:Agonist activity at human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 59nMAssay Description:Agonist activity at human CCK2R H7.39L mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R N2.61T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R T3.28V, T3.29S mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R I6.51V, F6.52Y mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R L7.39H mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I-CCK] from human CCK1R N2.61T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Displacement of [125I-CCK] from human CCK1R T3.28V, T3.29S mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [125I-CCK] from human CCK1R I6.51V, F6.52Y mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 676nMAssay Description:Displacement of [125I-CCK] from human CCK1R L7.39H mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of [125I-BDZ-2] from human CCK2R V3.28T, S3.29T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of [125I-BDZ-2] from human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I-BDZ-2] from human CCK2R H7.39L mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of [125I-CCK] from human CCK2R T2.61N mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 209nMAssay Description:Displacement of [125I-CCK] from human CCK2R V3.28T, S3.29T mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Displacement of [125I-CCK] from human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I-CCK] from human CCK2R H7.39L mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R M3.32A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R V3.36A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 269nMAssay Description:Displacement of [125I-BDZ-1] from human CCK1R W6.48A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Displacement of [125I-CCK] from human CCK1R M3.32A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [125I-CCK] from human CCK1R V3.36A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Displacement of [125I-CCK] from human CCK1R W6.48A mutant expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Agonist activity at human CCK1R V3.36A mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Agonist activity at human CCK1R W6.48A mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Displacement of [125I]-BDZ-1 from wild-type rat CCK1R expressed in COS cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Mayo Clinic
Curated by ChEMBL
Mayo Clinic
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]-BDZ-1 from rat CCK1R Ala-317,321,325 non dimerizing mutant expressed in COS cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 31.7nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 315nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12.2nMAssay Description:Displacement of [125I]CCK8 from rat CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 446nMAssay Description:Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23.6nMAssay Description:Displacement of [125I]-CCK-2 from human CCK1 receptor expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 977nMAssay Description:Partial agonist activity at wild-type human CCK2R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22.4nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair