BDBM50329198 2-(ethyl((5-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino)isothiazol-3-yl)methyl)amino)-2-methylpropan-1-ol::2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol::CHEMBL1232515::CHEMBL1650533

SMILES: CC[N@](Cc1cc(sn1)Nc2c3ncc(n3cc(n2)C)c4c[nH]nc4)C(C)(C)CO

InChI Key: InChIKey=RHGZQGXELRMGES-UHFFFAOYSA-N

Data: 27 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50329198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Testis-specific serine/threonine-protein kinase 2 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Nek2 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type IV (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Human)	BDBM50329198 (CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair