BDBM50329612 6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine::CHEMBL1270633

SMILES: CCc1c(c(nc(n1)N)N)C#CCc2cc(cc(c2)OC)c3ccccc3

InChI Key: InChIKey=QKLZHVMWTSBUFL-UHFFFAOYSA-N

Data: 1 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50329612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Staphylococcus aureus)	BDBM50329612 (6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Streptococcus pyogenes (Firmicutes))	BDBM50329612 (6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50329612 (6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Bacillus anthracis)	BDBM50329612 (6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	973	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Bacillus anthracis)	BDBM50329612 (6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair