BDBM50329705 (R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol::CHEMBL272502

SMILES CCC(CC)(c1ccc(OC[C@H](O)CO)c(C)c1)c1ccc(OC[C@@H](O)C(C)(C)C)c(C)c1

InChI Key InChIKey=AIKLCYAFOOBGEV-ZEQKJWHPSA-N

Data  2 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50329705   

TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329705((R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataKi:  740nMAssay Description:Binding affinity to VDR receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329705((R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329705((R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  120nMAssay Description:Vitamin-D activity at VDR receptor in human HL60 cells assessed as induction of cell differentiation by NBT reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329705((R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataIC50:  68nMAssay Description:Antiandrogen activity against androgen receptor in androgen-dependent mouse SC3 cells assessed as inhibition of testosterone-induced cell proliferati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329705((R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  83.2nMAssay Description:Effect on VDR transcriptional activity in human osteosarcoma cells in presence of 5% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329705((R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  15.6nMAssay Description:Effect on VDR transcriptional activity in human osteosarcoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329705((R)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  131nMAssay Description:Effect on VDR transcriptional activity in human Caco-2 cells in presence of 5% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed