BDBM50329706 (2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)propyl]-2-methylphenoxy}propane-1,2-diol::(S)-3-(4-(3-(4-((R)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol::CHEMBL272304
SMILES CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1
InChI Key InChIKey=AIKLCYAFOOBGEV-OZXSUGGESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50329706
Affinity DataKi: 12nMAssay Description:Binding affinity to VDR receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0400nMAssay Description:Activity at human VDR expressed in human HOS cells transfected with pGL3-hOc, pCDNA-hVDR and phRL-TK assessed as assessed as transcriptional activati...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0396nMAssay Description:Effect on VDR transcriptional activity in human osteosarcoma cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0400nMAssay Description:Agonist activity at human VDR expressed in HOS cells co-expressing human RXR by Dual-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Effect on VDR transcriptional activity in human Caco-2 cells in presence of 5% fetal calf serumMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antiandrogen activity against androgen receptor in androgen-dependent mouse SC3 cells assessed as inhibition of testosterone-induced cell proliferati...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as induction of transcriptional activity ...More data for this Ligand-Target Pair
Affinity DataEC50: 8.60nMAssay Description:Vitamin-D activity at VDR receptor in human HL60 cells assessed as induction of cell differentiation by NBT reduction assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:Effect on VDR transcriptional activity in human osteosarcoma cells in presence of 5% fetal calf serumMore data for this Ligand-Target Pair