BDBM50329832 5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide::CHEMBL1272187::N-alkylated benzimidazole derivative, 4a::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 4

SMILES: c1ccc2c(c1)ncn2CC(=O)c3ccc(c(c3)S(=O)(=O)N)Cl

InChI Key: InChIKey=XXDZSNJTAQNIAQ-UHFFFAOYSA-N

Data: 47 Kd  8 K_off  4 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 59 hits for monomerid = 50329832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.60E+5	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase 5B, mitochondrial (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	667	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 14 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	303	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	2.80E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.60E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.80E+6	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.140	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.840	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.270	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.08E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	670	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.140	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.270	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.840	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.11E+4	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50329832 (5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair