BDBM50329854 4-(benzyl(phenethyl)carbamoyl)-2-phenyl-1H-imidazole-5-carboxylic acid::CHEMBL1272245

SMILES OC(=O)c1nc([nH]c1C(=O)N(CCc1ccccc1)Cc1ccccc1)-c1ccccc1

InChI Key InChIKey=XJLNQOIHQWKQEL-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329854   

TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50329854(4-(benzyl(phenethyl)carbamoyl)-2-phenyl-1H-imidazo...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Pin1-mediated cyclin D1 expression in serum starved human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50329854(4-(benzyl(phenethyl)carbamoyl)-2-phenyl-1H-imidazo...)
Affinity DataIC50:  830nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50329854(4-(benzyl(phenethyl)carbamoyl)-2-phenyl-1H-imidazo...)
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of Pin1 in serum starved human PC3 cells assessed as reduction in insulin-induced p7)S6 kinase phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed