BDBM50329887 CHEMBL1271978::N-(6-(4-(allyloxy)-6-(trifluoromethyl)pyrimidin-2-yl)pyridin-3-yl)-2-chloroacetamide

SMILES FC(F)(F)c1cc(OCC=C)nc(n1)-c1ccc(NC(=O)CCl)cn1

InChI Key InChIKey=VXJHIIBUFJFRMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329887   

TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329887(CHEMBL1271978 | N-(6-(4-(allyloxy)-6-(trifluoromet...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329887(CHEMBL1271978 | N-(6-(4-(allyloxy)-6-(trifluoromet...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed