BDBM50330267 4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(5-piperazin-1-ylpyridin-2-yl)pyrimidin-2-amine::CHEMBL1230170::[4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-(5-piperazin-1-yl-pyridin-2-yl)-amine

SMILES: CC(C)c1n[nH]c(Cl)c1-c1ccnc(Nc2ccc(cn2)N2CCNCC2)n1

InChI Key: InChIKey=ZGJLAVYYTJNBMN-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50330267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50330267 (4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50330267 (4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50330267 (4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50330267 (4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Human)	BDBM50330267 (4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	467	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Human)	BDBM50330267 (4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50330267 (4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair