BDBM50330355 (1R,5S)-N-cyclopropyl-7-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)-N-(2,3-dimethylbenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide::(1R,5S)-N-cyclopropyl-7-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}-N-(2,3-dimethylbenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide::CHEMBL1230745

SMILES Cc1cc(Cl)c(OCCOc2ccc(cc2)C2=C([C@H]3CNC[C@@H](C2)N3)C(=O)N(Cc2cccc(C)c2C)C2CC2)c(Cl)c1

InChI Key InChIKey=VKBBVOVNGWGZCA-HVIPQOSHSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330355   

TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330355((1R,5S)-N-cyclopropyl-7-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50:  19nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330355((1R,5S)-N-cyclopropyl-7-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330355((1R,5S)-N-cyclopropyl-7-(4-(2-(2,6-dichloro-4-meth...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair