BDBM50330441 3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)butyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one::CHEMBL1278088

SMILES: Nn1c(CCCCN2CCN(CC2)c2ccc3ccccc3n2)nc2CCCCc2c1=O

InChI Key: InChIKey=WFQOETMVYMINSA-UHFFFAOYSA-N

Data: 1 KI  30 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50330441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A3 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Guinea pig)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22.3	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.93	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.40	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 5A (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Rat)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Guinea pig)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Neuropeptide Y receptor type 2 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Neuropeptide Y receptor type 1 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Neuromedin-K receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Substance-K receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histamine H1 receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Human)	BDBM50330441 (3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...) Show SMILES Show InChI	GoogleScholar	UniChem		4.72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair