BindingDB logo
myBDB logout

BDBM50330543 3-(4-methoxyphenylsulfonyl)-6-(piperazin-1-yl)-1H-indazole::CHEMBL1277287

SMILES: COc1ccc(cc1)S(=O)(=O)c1n[nH]c2cc(ccc12)N1CCNCC1

InChI Key: InChIKey=OLZQQVBWGYEYMU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330543   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50330543
PNG
(3-(4-methoxyphenylsulfonyl)-6-(piperazin-1-yl)-1H-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)c1n[nH]c2cc(ccc12)N1CCNCC1
Show InChI InChI=1S/C18H20N4O3S/c1-25-14-3-5-15(6-4-14)26(23,24)18-16-7-2-13(12-17(16)20-21-18)22-10-8-19-9-11-22/h2-7,12,19H,8-11H2,1H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
124n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells


J Med Chem 53: 7639-46 (2010)


Article DOI: 10.1021/jm1007825
BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
More data for this
Ligand-Target Pair