BDBM50330574 1-(3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl)piperidine-4-carboxylic acid::CHEMBL1277019
SMILES CCc1ccsc1-c1cnc(N)c(n1)N1CCC(CC1)C(O)=O
InChI Key InChIKey=SXVAXEOOBRDRSC-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50330574
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of NEK2 by microfluidic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of NEK2 autophosphorylation after 2 hrs by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMT: 2°CAssay Description:Inhibition of PLK1 after 75 mins at room temperature by caliper methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of NEK2 assessed as inhibition of substrate phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.25E+4nMT: 2°CAssay Description:Inhibition of NEK1 after 1 hr at room temperature by caliper methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair