BDBM50330686 5-(furan-2-ylmethyl)-4-methyl-2-phenyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1277031

SMILES Cc1n(Cc2ccco2)c(=O)cc2[nH]n(-c3ccccc3)c(=O)c12

InChI Key InChIKey=MIRFIMNUTDFIPW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330686   

TargetNADPH oxidase 4(Human)
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330686(5-(furan-2-ylmethyl)-4-methyl-2-phenyl-1H-pyrazolo...)
Affinity DataKi:  9.49E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed