BDBM50330722 2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1276946

SMILES: Cc1n(Cc2ccccn2)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12

InChI Key: InChIKey=DNKYHHFCPXKFIY-UHFFFAOYSA-N

Data: 4 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50330722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 4 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NADPH oxidase 1 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome b-245 heavy chain (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NADPH oxidase 5 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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NADPH oxidase 4 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		165	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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NADPH oxidase 1 (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		165	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome b-245 heavy chain (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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