BDBM50330790 CHEMBL1277594::N-Methyl-3-phenyl-3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-propan-1-amine

SMILES CNCCC(c1ccccc1)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=JOSMNLLYOHOBPW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50330790   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed