BDBM50330793 2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one::CHEMBL1275969

SMILES CC(C)c1ccccc(=O)c1O

InChI Key InChIKey=TUFYVOCKVJOUIR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50330793   

TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataKi:  3.30E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataKi:  9.50E+3nMAssay Description:Binding affinity to mushroom Tyrosinase using L-DOPA as substrate assessed as inhibition constant by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 9.53E+3nMAssay Description:Inhibition of mushroom tyrosinase after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 9.53E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 9.53E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 9.53E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosinase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed