BDBM50330896 CHEMBL1277419::trans rac-N1-(4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)-N2-(4-(trifluoromethyl)benzyl)ethane-1,2-diamine

SMILES Cc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCc2ccc(cc2)C(F)(F)F)c1

InChI Key InChIKey=VNRFDXWZGVRTLB-LPHOPBHVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330896   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330896(CHEMBL1277419 | trans rac-N1-(4-((6-amino-4-methyl...)
Affinity DataKi:  740nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330896(CHEMBL1277419 | trans rac-N1-(4-((6-amino-4-methyl...)
Affinity DataKi:  4.04E+4nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330896(CHEMBL1277419 | trans rac-N1-(4-((6-amino-4-methyl...)
Affinity DataKi:  6.12E+4nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed