BDBM50330897 6-(((3R,4S)-4-(2-(4-fluorobenzylamino)ethoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine trihydrochloride::CHEMBL1233765::CHEMBL1278133

SMILES Cc1cc(N)nc(C[C@H]2CNC[C@@H]2OCCNCCc2cccc(F)c2)c1

InChI Key InChIKey=NESZTSPBRDBHCW-PXNSSMCTSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50330897   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330897(6-(((3R,4S)-4-(2-(4-fluorobenzylamino)ethoxy)pyrro...)
Affinity DataKi:  63nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330897(6-(((3R,4S)-4-(2-(4-fluorobenzylamino)ethoxy)pyrro...)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330897(6-(((3R,4S)-4-(2-(4-fluorobenzylamino)ethoxy)pyrro...)
Affinity DataKi:  1.87E+7nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330897(6-(((3R,4S)-4-(2-(4-fluorobenzylamino)ethoxy)pyrro...)
Affinity DataKi:  3.62E+7nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair