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BDBM50330926 2-[(p-Chlorophenylthio)propylide-1-enehydrazinyl]-5-methylthiazolidin-4-one::CHEMBL1276253

SMILES: Cc1sc(N=NCCCSc2ccc(Cl)cc2)nc1O

InChI Key: InChIKey=ZKVVWNNTYZCGMS-BMRADRMJSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330926   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cruzipain


(Trypanosoma cruzi)
BDBM50330926
PNG
(2-[(p-Chlorophenylthio)propylide-1-enehydrazinyl]-...)
Show SMILES Cc1sc(N=NCCCSc2ccc(Cl)cc2)nc1O
Show InChI InChI=1S/C13H14ClN3OS2/c1-9-12(18)16-13(20-9)17-15-7-2-8-19-11-5-3-10(14)4-6-11/h3-6,18H,2,7-8H2,1H3/b17-15+
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Federal University of Pernambuco

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 mins


Bioorg Med Chem 18: 7826-35 (2010)


Article DOI: 10.1016/j.bmc.2010.09.056
BindingDB Entry DOI: 10.7270/Q2CV4J17
More data for this
Ligand-Target Pair