BDBM50331025 (Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-(2-diethylamino-ethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one::CHEMBL1278233
SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(Br)cc34)c(C)c2C1=O
InChI Key InChIKey=XDDLRMCIDZLHNL-LGMDPLHJSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50331025
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair